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How ONKONEK Works

Image by National Cancer Institute

THE NATURE OF THE BEAST

Cancer is like an out of control car

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The accelerator is jammed on and the brakes don’t work

Effects on the normal cell of genetic cancer causing mutations

NORMAL CELLS WITH ONCOGENIC GENETIC MISTAKES SELF-DESTRUCT (APOPTOSIS)

Apoptosis is committing suicide which is an act requiring energy

CANCER CELLS AVOID APOPTOSIS

They do this by restricting their available energy so there is

 not enough for them to kill themselves

Strip 2

Cancer cells are addicted to division.
Without sufficient energy normal cells stop dividing.
Onkonek lowers the energy just enough so cancer cells die as they divide.

Turning Down the Energy of Cancer Cells

Cancer cells have to closely control the energy molecule ATP inside them. Too much energy and they commit suicide (Apoptosis). Too little energy and they are not able to survive (Necrosis).

 

ONKONEK  turns down the energy controlling “Thermostat” much lower than the cancer cell needs or can tolerate. There is not enough energy to maintain important normal functions including the pumps that maintain the gradient across the cell membrane so that the cell effectively “drowns”.

NECROSIS

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Low Energy

APOPTOSIS

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High Energy

SYNTHERIX’s lead agent ONKONEK works in a novel way which should avoid the side-effects of chemotherapy and immunotherapy because it does not affect normal cells.
 
ONKONEK also has a broad global effect against most different types of cancer.

avoid side effects
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